A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia - ScienceDirect
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Descrição
Inhibition of the Menin (MEN1) and MLL (MLL1, KMT2A) interaction is a potential therapeutic strategy for MLL-rearranged (MLL-r) leukemia. Structure-ba…
The menin-MLL1 interaction is a molecular dependency in NUP98
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression
Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors
Frontiers Rewiring the Epigenetic Networks in MLL-Rearranged
High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage
Recruitment of MLL1 complex is essential for SETBP1 to induce
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression
MLL::AF9 degradation induces rapid changes in transcriptional
Epigenetic deregulation in myeloid malignancies - ScienceDirect
Pharmacologic Inhibition of the Menin-MLL Interaction Blocks
Pharmacologic Inhibition of the Menin-MLL Interaction Blocks
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