Genes that Escape Silencing on the Second X Chromosome May Drive Disease
Por um escritor misterioso
Descrição
When X-linked genes evade silencing on the “inactive” chromosome in XX cells, some protect women from diseases such as cancer, but others seem to promote conditions such as autoimmunity.
Frontiers Escape From X-Chromosome Inactivation: An Evolutionary Perspective
X-Chromosome Inactivation and Skin Disease - ScienceDirect
X-linked gene dosage contributes to sex disparities in disease.
Variability in dosage compensation on the X chromosome. A: The X and Y
Frontiers Escape From X-Chromosome Inactivation: An Evolutionary Perspective
PDF) Long noncoding RNA XIST: Mechanisms for X chromosome inactivation, roles in sex-biased diseases, and therapeutic opportunities
Genes that escape from X‐chromosome inactivation: Potential contributors to Klinefelter syndrome - Navarro‐Cobos - 2020 - American Journal of Medical Genetics Part C: Seminars in Medical Genetics - Wiley Online Library
Genes, Free Full-Text
Cross-species examination of X-chromosome inactivation highlights domains of escape from silencing, Epigenetics & Chromatin
Cells, Free Full-Text
Escape genes are marked by unique mCG and mCH patterns. (A)
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