GPC2-CAR T cells tuned for low antigen density mediate potent
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Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
Full article: B7-H3-targeted CAR-T cell therapy for solid tumors
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours. - Abstract - Europe PMC
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Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors
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GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice - ScienceDirect
JCM, Free Full-Text
A chimeric antigen receptor uniquely recognizing MICA/B stress proteins provides an effective approach to target solid tumors - ScienceDirect
Mechanisms of Resistance and Treatment of Relapse after CAR T-cell Therapy for Large B-cell Lymphoma and Multiple Myeloma - Transplantation and Cellular Therapy, Official Publication of the American Society for Transplantation and
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